- 18 Oct 2021
- Reading time
- 4 minutes
Our immune system is a labyrinth of different cells, organs, tissues, and proteins that defends the internal system against invaders. It is the Immune system that shields the body against numerous potential attacks of viruses, bacteria, and parasites, and many more lethal trespassers.
This article gives an overview of the factors that can help boost your immune system by directly supplementing with Urolithin A. For this you could consider using a supplement to get the nutrient that helps in nourishing the cells and giving them a natural vigor to function comme il faut. Want to know more? We’ll tell you all about Urolithin A and how to supplement it.
What is Urolithin A?
Urolithin A is a naturally derived nutrient which is processed by microflora (bacteria and microscopic algae dwelling at a particular site). Proven to restore mitochondrial health and intensify robustness in old age people, animals, and clinical models. Taking a supplement for this nutrient is necessary as not everyone nowadays is capable of producing it naturally. Research revealed that only 12% of people were proficient in forming Urolithin A naturally.
Benefits of Urolithin A
Urolithin benefits old age people and helps in increasing their lifespan up to 49%, as discerned by the experiments. Apart from that mentioned below are some of the benefits it causes to the overall health system.
Anti-cancer: Studies conducted for the anti-cancer properties of Urolithin and the researchers were able to find out that Urolithin A helps in avoiding cancer like kidney, colon, prostate, breast, bladder, and liver cancer by blocking the cell cycle and preventing the cell growth that presented a role in spreading cancer.
Improves cardiac functions: Urolithin A helps restore heart mitochondria and prevents cardiac inflammation in patients with cardiovascular disease by preventing the blockage of blood vessels.
Reduced cell death: Urolithin A was tested on a rat to claim that it reduces cell death in species as it helps in nourishing mitochondria and produces new and healthy cells that work fittingly and, the overall healthy body results in less cell death.
Cholesterol reduction: Tested in a rat with an aortic injury( when the aorta receives laceration due to some force exerted on the artery), it explicated that notwithstanding the high cholesterol dosage to the animal, the Urolithin caused a decrease in LDLs that is mounting cholesterol level due to certain genetic factors.
Help prevent mitochondrial culmination and muscle dysfunction: Urolithin A helps in muscle reignition and improves the declining mitochondrial functions in aged people. People given doses between 250 mg to 1000 mg showed no side effects. Four weeks after regular dosage showed improved muscle strength and cell function.
In what food can Urolithin A be found?
Urolithin is present in the following food in specific quantities:
Some fruits like raspberries, blackberries, pomegranate, strawberries and strawberries jam, cloudberries, rosehip, boysenberries contain Urolithin A. In seeds, Urolithin A is present in mango seeds and Black raspberries seeds.
In nuts, pecans and walnuts contain generous amounts of Urolithin A.
In beverages, Pomegranate juices, Whiskey, cognac, and Oak-aged red wine sustain a fair amount of Urolithin A.
These foods are the sources of Urolithin A but it is not specifically made from these foods. So consuming these foods will not guarantee the direct formation of Urolithin A in many cases. Some sources of ellagitannins which form Urolithin are nuts, some berries (strawberries, blackberries, and cloudberries).
Supplementation regarding Urolithin A
It is advised to take two capsules per day by the physician but, it depends on the doctor who prescribes. Supplement of Urolithin A is not advised for pregnant and nursing women as per research. For Gut microbiome differences and lack of diet that leads to Urolithin A, supplementation is recommended by the physicians to overcome the lack of Urolithin in the human body. Urolithin supplements come in powder, tablet, and capsule form.
Supplement often used for Urolithin A that is available in the market is Urolithin a Supplement | Strength | Celltrient. This supplement supports cellular health and processes to replenish mitochondria. Also, it helps in releasing elements that help in building and strengthening muscle cells. Also, this dietary supplement contains elements like Urolithin A (as Mitopure) that is known for its properties to support mitochondrial cells in muscles. Other ingredients present in the tablets are Sunflower lecithin, Glycerol Monostearate, Polysorbate 80, medium-chain triglycerides, and several other components to help improve digestion, preserve quality or package the supplement.
Mitochondrial health is a crucial factor in the cell life cycle and people of any age group as it is associated with the whole body's wellness. Several genetic diseases can cause a decline in Mitochondrial health which can be a threat to general health. To nourish the mitochondria present in cells and to help the muscles work properly in old age people, Urolithin A is an essential mitochondrial health supplement and is widely recommended by doctors to reduce vitality issues.
 Mukku, Murray, Espin, & Perdew (2018), “Urolithin A Is a Dietary Microbiota-Derived Human Aryl Hydrocarbon Receptor Antagonist”, NCBI
 Singh, Andreux, Blanko, Auwerx, & Rinsch (2019), “Urolithin A, a Gut Microbiome Derived Metabolite”, Academic
 D’Amico, Andreux, Valdes, Singh, Rinsch, & Awerex (2021), “Impact of the Natural Compound Urolithin A on Health, Disease, and Aging”, Science Direct
 Aebischer, Blanco-bose, Kern, Dunngalvin, Andreux, D’Amico, Singh, & Rinsch (2021), “Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability”, Nature